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Research Projects


The focus of the BIOMATCELL research programme was originally defined in a series of meetings with academic research groups and Swedish industrial companies already during the planning of the original proposal for BIOMATCELL in 2006. The selection criteria of the areas comprising the research programme of BIOMATCELL were: (i) highest international scientific standard, (ii) identified clinical needs and potential for innovative development and industrial realization and (iii) emerging technologies.

The overall aim of the research programme is to to generate new ideas and concepts for clinical treatments based on biomaterials or biomaterials associated cell therapy, with a focus on applications in the musculoskeletal system. The research addresses the following clinical needs/challenges:

• faster bone healing for load-bearing implants
• improved implant fixation in compromised tissues (e.g. osteoporosis)
• bone augmentation and bone defect repair
• reliable soft tissue penetration for percutaneous devices
• infection control and antibacterial surfaces

The platform for research consists of the competencies and the state-of-the-art and emerging technologies available in the laboratories of the partners involved in BIOMATCELL. The tools include an array of technologies and methodologies, including preparative and analytical techniques allowing atomic/molecular level control of materials properties, modern molecular and cell biology techniques, well characterized cell lines, different in vitro and in vivo models for studying biomaterial-cell interactions, as well as access to clinical studies.

The research programme currently consists of the following six projects:

1. Free form fabricated implant materials – Biological mechanisms and optimization of tissue response by pore structure and surface modification. (ADDITIVE MANUFACTURING)

2. Osseointegration of tailored ceramic-titanium implants for craniomaxillofacial applications. (BIOCERAMIC)

3. New models and methods for studying infection – Development of new concepts for infection control in clinical applications (INFECTION CONTROL)

4. Nanofabricated model surfaces with systematically varied surface topography. (NANO)

5. Guided Bone Regeneration (GBR) and bone substitutes in the reconstruction of the atrophic jaw. Tissue dynamics and clinical aspects. (NEOGEN)

6. Bone and cartilage regeneration. (OSTEOCHONDRAL)





Contact Information


P.O. Box 412, SE-405 30 Göteborg

Visiting Address:
Arvid Wallgrens backe 20, 7th floor

Page Manager: Maria Hoffman|Last update: 4/27/2016

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Utskriftsdatum: 2018-02-20